References (selection) Reference Detail URL Summary Apoptosis / liver (in vitro) PMC4882837 (2016) PMC Apoptosis + inhibition of proliferation on hepatic tumor cells in culture. Bladder (in vitro) Scientific Reports 2021; PMID 34799663 PubMed Cytotoxicity, apoptosis and cycle arrest; selectivity vs. normal cells. Breast/lung (in vitro) Pak J Pharm Sci 2019 PDF IC 50 ~0.73 (MCF-7) / 1.10 mg/mL (A549). Ovary (in vitro) Discover Oncology 2025 Article Fulvic acid: decreases proliferation/migration/invasion via CYP1A1. NSCLC (mouse) Heliyon 2023 PDF Fulvic acids: tumor inhibition via COX-2 / PGE 2 / EP4. Ovarian radioprotection (rat) PMID 26530234 PubMed Tissue protection signal against radiation (animal model). Osteosarcoma + chemo (rat) PMID 35957703 PubMed Hepatorenal attenuation in co-administration; no human data. DAPs: benefits/risks Int J Mol Sci 2021;22(23):13063 MDPI Overview of dibenzo-α-pyrones (urolithins vs alternariol: toxicological issues). EU Contaminants Framework Regulation (EU) 2023/915 EUR-Lex Maximum levels of contaminants (including heavy metals) in foodstuffs. Warning The information presented is for educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Before using any supplement or changing your lifestyle, please consult a healthcare professional . In the context of cancer: coordination essential with the healthcare team .
